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Related Concept Videos

Quality Control01:05

Quality Control

Quality control is one of the three cyclical quality assurance activities that help keep a system under statistical control. Typical quality control activities include creating quality control charts, conducting proficiency testing, and documenting and archiving results.
Quality control helps track data, visualize trends, and identify variations, making it easier to detect deviations that may affect the accuracy of an analysis. One way to do this is by generating a quality control chart, which...
Quality Assurance01:19

Quality Assurance

Quality assurance is the overarching term used to describe the activities employed to ensure the proper performance of a system. These activities can be classified into three categories: quality control, quality assessment, and internal corrective measures. Typically, these activities work cyclically: quality control is performed before and during the analysis, while quality assessment occurs during and after the investigation. Internal corrective measures are implemented based on the findings...
Coagulation01:06

Coagulation

Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...
Coagulation01:09

Coagulation

The coagulation phase is a critical part of the body's process to prevent blood loss following injury to blood vessels. It involves chemical reactions that form a clot to seal the injured area. The clotting process begins shortly after injury, within 15-20 seconds for severe damage and 1-2 minutes for minor injuries.
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...

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Related Experiment Video

Updated: Jun 26, 2026

The Nijmegen Hemostasis Assay: Simultaneous Fluorogenic Measurement of Thrombin and Plasmin Generation in a Single Well
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The Nijmegen Hemostasis Assay: Simultaneous Fluorogenic Measurement of Thrombin and Plasmin Generation in a Single Well

Published on: February 27, 2026

[The quality control in the coagulation laboratory].

Adriana Aurelia Ruiz-de-Chávez-Ochoa1, Evangelina Núñez-Pérez, Beatriz Muñoz-Muñoz

  • 1Unidad de Investigación Médica en Trombosis, Hemostasia y Aterogénesis, Hospital General Regional 1 "Gabriel Mancera," Instituto Mexicano del Seguro Social, Distrito Federal, México.

Revista Medica Del Instituto Mexicano Del Seguro Social
|January 10, 2009
PubMed
Summary

Ensuring quality in coagulation tests is crucial for accurate medical findings. This review highlights preanalytic errors and quality control programs to improve diagnostic reliability in hemostasis.

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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

Related Experiment Videos

Last Updated: Jun 26, 2026

The Nijmegen Hemostasis Assay: Simultaneous Fluorogenic Measurement of Thrombin and Plasmin Generation in a Single Well
08:01

The Nijmegen Hemostasis Assay: Simultaneous Fluorogenic Measurement of Thrombin and Plasmin Generation in a Single Well

Published on: February 27, 2026

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

Area of Science:

  • Clinical Pathology
  • Laboratory Medicine
  • Hematology

Context:

  • Coagulation testing is essential for diagnosing and managing bleeding and thrombotic disorders.
  • Laboratory results require interpretation to become clinically relevant medical findings.
  • Advances in technology and the significance of hemostatic events necessitate rigorous quality assessment.

Purpose:

  • To provide a comprehensive review of potential errors in coagulation tests.
  • To emphasize the importance of quality control throughout the entire testing cycle, from physician request to clinical interpretation.
  • To highlight the critical role of preanalytic factors in achieving reliable hemostasis test results.

Summary:

  • Identifies various sources of error in coagulation testing, including issues with samples, methods, instruments, reagents, and personnel.
  • Stresses that analytical results are scientific facts that must be interpreted within a clinical context.
  • Advocates for high-quality blood collection procedures and awareness of preanalytic errors to ensure accurate outcomes.
  • Underscores the mandatory nature of both internal and external quality control programs in laboratory diagnostics.

Impact:

  • Improved accuracy and reliability of coagulation test results.
  • Enhanced clinical decision-making based on dependable hemostasis data.
  • Reduced risk of misdiagnosis and inappropriate treatment for patients with hemostatic disorders.
  • Establishment of a standardized framework for quality management in coagulation laboratories.