Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...
Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Treatment Strategies for Psychological Disorders01:24

Treatment Strategies for Psychological Disorders

Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Understanding adolescents' perspectives on suicide risk screening in primary care: Implications and insights for implementation and practice.

PLOS mental health·2026
Same author

Benthic habitat structure explains broad-scale patterns in reef fish communities.

Ecological applications : a publication of the Ecological Society of America·2026
Same author

Editorial: When, Where, and for Whom Does Behavioral Activation Work? Optimizing Treatment for Adolescent Depression.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same author

Quality Improvement: Disseminating Pragmatic Approaches to Advancing Pediatric Mental Health Care.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same author

Behavioral Activation as a Principle-Based Treatment: Developments from a Multi-Site Collaboration to Advance Adolescent Depression Treatment.

Evidence-based practice in child and adolescent mental health·2026
Same author

Digital Attention Bias in Cancer Survivors Intervention for Adolescent and Young Adult Cancer Survivors: Protocol for a Pilot Randomized Controlled Trial.

JMIR research protocols·2026

Related Experiment Videos

Collaborative care for adolescent depression: a pilot study.

Laura Richardson1, Elizabeth McCauley, Wayne Katon

  • 1Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98115, USA. laura.richardson@seattlechildrens.org

General Hospital Psychiatry
|January 13, 2009
PubMed
Summary
This summary is machine-generated.

This pilot study shows that a collaborative care intervention is feasible and acceptable for treating depression in youth primary care settings. The model improved depressive symptoms in 74% of adolescents, similar to adult intervention outcomes.

Related Experiment Videos

Area of Science:

  • Adolescent Psychiatry
  • Primary Care Medicine
  • Mental Health Services Research

Background:

  • Depression in youth is a significant public health concern.
  • Primary care settings are crucial for early identification and intervention.
  • Existing interventions for youth depression in primary care require further development and evaluation.

Purpose of the Study:

  • To assess the feasibility and acceptability of a collaborative care intervention for adolescent depression in primary care.
  • To explore preliminary treatment outcomes for youth receiving collaborative care.
  • To adapt and apply the IMPACT model for adult depression to an adolescent population.

Main Methods:

  • Pilot intervention study conducted in three primary care clinics.
  • Utilized a collaborative care model with a nurse depression care manager (DCM) and mental health specialist oversight.
  • Intervention included patient/parent education, self-management support, and choice of medication or therapy.
  • Participants (n=40, ages 12-18) were assessed for 6 months using the Patient Health Questionnaire (PHQ-9).

Main Results:

  • 87% of youth completed the 6-month intervention.
  • 74% of participants achieved a 50% or greater reduction in depressive symptoms (PHQ-9).
  • High satisfaction reported by youth, parents, and physicians.
  • Intervention adapted from adult models showed comparable outcomes.

Conclusions:

  • The collaborative care model is feasible and highly acceptable for adolescents and parents in primary care.
  • The intervention demonstrates promising efficacy in improving depressive outcomes for youth.
  • Further evaluation in a randomized controlled trial is warranted.