Related Experiment Video
Updated: Jun 26, 2026

07:51
Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice
Published on: January 13, 2012
Adventitial stripping for carotid sinus syndrome
R J Toorop1, M R M Scheltinga, F L Moll
1Department of Surgery, Máxima Medical Center, Veldhoven, The Netherlands. rtoorop@yahoo.com
Annals of Vascular Surgery
|January 13, 2009
Summary
Carotid sinus syndrome (CSS) causes dizziness and fainting due to baroreflex issues. Surgical carotid denervation, or adventitial stripping, effectively treats all CSS types with a high success rate and low complications.
Area of Science:
- Neurology
- Cardiology
- Vascular Surgery
Background:
- Carotid sinus syndrome (CSS) involves exaggerated carotid baroreflex responses, leading to syncope and dizziness.
- Existing treatments like pacemakers are primarily effective for the cardioinhibitory type of CSS.
- A need exists for treatments addressing all CSS subtypes.
Purpose of the Study:
- To review the efficacy and safety of surgical adventitial stripping of the carotid sinus for treating CSS.
- To evaluate this surgical approach across different types of carotid sinus syndrome.
Main Methods:
- Analysis of data from 130 surgical procedures involving adventitial stripping of the carotid sinus.
- Review of patient outcomes, including symptom relief and complication rates.
Main Results:
- Adventitial stripping demonstrated effectiveness in 85% of patients with CSS.
- The surgical technique showed low complication rates.
- Transient blood pressure and heart rate alterations were noted postoperatively, necessitating monitoring.
Conclusions:
- Surgical carotid denervation via adventitial stripping is a highly effective treatment for all forms of carotid sinus syndrome.
- This surgical intervention offers a viable alternative to pacemakers, particularly for vasodepressor and mixed CSS types.
- Close postoperative monitoring is essential to manage potential transient hemodynamic changes.