Upper respiratory tract infections (including otitis media)
1Child Health Division, Menzies School of Health Research, Casuarina, NT 0811, Darwin, Australia. peterm@menzies.edu.au
Insights
Most childhood upper respiratory tract infections resolve without treatment. This review helps clinicians understand evidence-based interventions for pediatric respiratory infections, guiding families on appropriate care and managing distress.
Area of Science:
- Pediatrics
- Infectious Diseases
- Evidence-Based Medicine
Background:
- Upper respiratory tract infections (URTIs), including otitis media, are highly prevalent in children.
- While often mild, URTIs cause significant distress due to frequency, fever, and constitutional symptoms.
- Clinicians require evidence to guide families on managing pediatric respiratory infections.
Purpose of the Study:
- To synthesize evidence on the natural course of pediatric URTIs.
- To identify interventions evaluated in high-quality studies for URTIs.
- To assess the effectiveness and magnitude of benefit for these interventions.
Main Methods:
- Systematic review of high-quality studies on pediatric URTIs.
- Analysis of outcomes for children receiving no additional treatment.
- Evaluation of interventions and their reported benefits.
Main Results:
- Most pediatric URTIs are self-limiting without specific interventions.
- Several interventions have been assessed in well-designed studies.
- The overall benefit of specific interventions varies and requires careful consideration.
Conclusions:
- Evidence-based guidance is crucial for managing pediatric URTIs and associated family distress.
- Understanding the natural history and intervention efficacy aids clinical decision-making.
- Informed advice empowers families and optimizes care for children with respiratory infections.
Abstract:
Upper respiratory tract infections (including otitis media) are the most common illnesses affecting children. Most illnesses are mild and resolve completely without specific treatment, but the frequency of infection and association with fever and constitutional symptoms creates significant distress for the child and the family. By understanding the evidence available from high-quality studies, the clinician can advise the families on appropriate action. The goal of this article is to support clinicians in answering the following questions: (1) What happened to children with these conditions when no additional treatment was provided? (2) Which interventions have been assessed in well-designed studies? (3) Which interventions have been shown to improve outcomes? (4) How large is the overall benefit?
Related Concept Videos
Microbiota of the Respiratory Tract
Anatomy of Respiratory System I: Upper Respiratory Tract
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
Common Respiratory Disorders
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Overview of Respiratory System
What is the Respiratory System?
The respiratory system consists of a series of organs responsible for taking in oxygen and expelling carbon dioxide. The primary function of the respiratory system is to...


