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Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
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Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
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Cystic Fibrosis: Pathogenesis

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The Bronchial Tree

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Cystic Fibrosis: Management

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Sinus disease and chronic sinusitis...
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Related Experiment Videos

Bronchiectasis in children.

Gregory J Redding1

  • 1Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195-6320, USA. gredding@u.washington.edu

Pediatric Clinics of North America
|January 13, 2009
PubMed
Summary
This summary is machine-generated.

This article provides guidance on chronic treatment strategies for bronchiectasis, a lung condition causing persistent cough and infections. It covers both cystic fibrosis and non-cystic fibrosis causes, focusing on outpatient management.

Related Experiment Videos

Area of Science:

  • Pulmonology
  • Respiratory Medicine

Background:

  • Bronchiectasis is a chronic airway disease characterized by persistent cough, recurrent infections, and airflow obstruction.
  • It affects both children and adults, stemming from various underlying causes.

Purpose of the Study:

  • To provide grading and recommendations for chronic therapies in bronchiectasis.
  • To focus on outpatient management for both cystic fibrosis-related and non-cystic fibrosis-related bronchiectasis.

Main Methods:

  • Review and synthesis of current evidence on chronic bronchiectasis therapies.
  • Development of grading and recommendations for clinical practice.

Main Results:

  • Established grading for chronic therapies.
  • Provided specific recommendations for managing bronchiectasis in outpatient settings.
  • Differentiated treatment approaches for CF- and non-CF-related bronchiectasis.

Conclusions:

  • Effective chronic outpatient management is crucial for improving outcomes in bronchiectasis.
  • Tailored therapeutic strategies are necessary for CF- and non-CF-related bronchiectasis.