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Co-morbid association of depression and COPD: a population-based study
Tze-Pin Ng1, Mathew Niti, Calvin Fones
1Gerontological Research Programme, Faculty of Medicine, National University of Singapore (NTP, MN), National University Hospital, 5 Lower Kent Ridge Road, Singapore. pcmngtp@nus.edu.sg
Respiratory Medicine
|January 13, 2009
Summary
Depression is common in COPD patients and is independently linked to worse health and daily functioning. This study highlights the significant impact of depressive symptoms on managing chronic obstructive pulmonary disease.
Area of Science:
- Pulmonary Medicine
- Psychiatry
- Gerontology
Background:
- Depression is frequently observed in patients with Chronic Obstructive Pulmonary Disease (COPD).
- The independent relationship between depression and COPD, and its impact on COPD outcomes, requires further elucidation.
Purpose of the Study:
- To investigate the independent association between depression and COPD.
- To examine the effect of depressive symptoms on health status and functional outcomes in COPD patients.
Main Methods:
- A population-based study involving 2402 Chinese adults aged 55 and above.
- Assessment included COPD diagnosis, Geriatric Depression Scale, Activities of Daily Living (ADL) dependence, SF-12 health status, smoking, and medication use.
Main Results:
- COPD patients exhibited a higher prevalence of depressive symptoms (22.8%) compared to non-COPD individuals (12.4%), with an adjusted odds ratio of 1.86.
- Among COPD patients, those with depression reported significantly higher rates of ADL disability, poorer self-rated health, and worse physical and mental component scores on the SF-12.
Conclusions:
- Depressive symptoms are independently associated with COPD, even after controlling for confounding factors.
- In individuals with COPD, the presence of depressive symptoms correlates with diminished health and functional status, impacting self-management.
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