Related Experiment Video
Updated: Jun 26, 2026

06:11
Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring
Published on: May 21, 2017
Severe hemorrhage from a hypodermoclysis site
Shane O'Hanlon1, Patricia Sheahan, Robert McEneaney
1Kerry General Hospital, Tralee, Co Kerry, Ireland. sohanlon@gmail.com
The American Journal of Hospice & Palliative Care
|January 13, 2009
Summary
Hypodermoclysis, a method of subcutaneous fluid infusion, is generally low-risk. However, this case report details a patient death potentially linked to this procedure, highlighting a rare but serious complication.
Area of Science:
- Geriatrics
- Palliative Care
- Clinical Procedures
Background:
- Hypodermoclysis involves subcutaneous fluid administration, often used in elderly or terminally ill patients.
- This method is typically considered a safe alternative when intravenous access is challenging.
- It offers a less invasive route for fluid and medication delivery.
Observation:
- A case study involving a patient undergoing hypodermoclysis is presented.
- The patient experienced an adverse event during or following the procedure.
- This event raises questions about the safety profile of hypodermoclysis.
Findings:
- The patient's death is potentially associated with the hypodermoclysis procedure.
- This suggests a rare but severe complication may arise from subcutaneous fluid infusion.
- Further investigation into the causal link is warranted.
Implications:
- Clinicians should be aware of the potential risks associated with hypodermoclysis, even if rare.
- This case underscores the importance of careful patient selection and monitoring during subcutaneous fluid therapy.
- It may prompt a review of protocols for hypodermoclysis to mitigate risks.
Related Concept Videos
Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Epistaxis
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Esophageal Varices-II: Clinical Features and Management
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Introduction to Hemostasis
Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
Disorders of Hemostasis
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.

