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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Cognitive and behavioral status of low birth weight preterm children raised in a developing country at preschool age
Júlia L do Espírito Santo1, Mirna W Portuguez, Magda L Nunes
1Divison of Neurology, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.
Insights
Preterm and low birth weight children in developing countries show higher rates of cognitive and behavioral issues by preschool age. These findings highlight the need for early intervention and support for vulnerable children.
Area of Science:
- Developmental Pediatrics
- Neuropsychology
- Global Health
Background:
- Preterm birth and low birth weight are significant risk factors for adverse neurodevelopmental outcomes.
- Children in developing countries often face additional challenges impacting development.
- Early assessment is crucial for identifying and addressing developmental delays.
Purpose of the Study:
- To evaluate the cognitive and behavioral development of preterm and low birth weight children at preschool age.
- To identify specific areas of developmental vulnerability in this population.
- To explore the relationship between birth characteristics and developmental outcomes in a developing country context.
Main Methods:
- Prospective cross-sectional study involving 80 preterm and low birth weight neonates from Brazil.
- Neuropsychological assessments at 4-5 years included Wechsler Preschool and Primary Scale of Intelligence (WPPSI) and Conners' Parent Rating Scale-Revised.
- Denver test, neurological examination, and review of perinatal data were utilized.
Main Results:
- Children exhibited lower average IQ scores, particularly in visual-motor coordination and reasoning speed.
- Significant percentages showed abnormal results in arithmetic (32.5%) and attention deficit/hyperactivity disorder (ADHD) behaviors (48%).
- Lower scores on developmental scales and abnormal neurological exams were associated with lower IQ and ADHD.
Conclusions:
- Preterm and low birth weight children raised in developing countries demonstrate an elevated incidence of cognitive and behavioral disorders.
- These findings underscore the long-term impact of prematurity and low birth weight on child development.
- Targeted interventions are necessary to mitigate these developmental challenges.
Objective:
To assess cognitive and behavioral development at preschool age of children born preterm and with low birth weight and raised in a developing country.
Methods:
Prospective cross-sectional study of 80 neonates born in a university hospital in southern Brazil. Neuropsychological assessment at age 4-5 years included the Wechsler Preschool and Primary Scale of Intelligence (WPPSI), Conners' Parent Rating Scale-Revised, Denver test and neurological examination. Perinatal and early neuropsychomotor development information was collected from the database during follow-up. Results were related to birth weight, sex and gestational age.
Results:
WPPSI scores were: total intelligence quotient (IQ) 88.00+/-16.96, verbal IQ 89.72+/-16.72, and executive IQ 88.12+/-15.71 for the group with less than 1,500 grams; and total IQ 91.11+/-14.73, verbal IQ 93.36+/-12.65, and executive IQ 90.20+/-16.06 for the group between 1,500 and 2,500 grams. The best scores were obtained in tests that evaluated capacity of abstraction and symbolization, picture completion and common perception, in which only 5% and 6.3% of the children had abnormal results, respectively. The lowest scores were obtained in tests that evaluated visual-motor coordination and flexibility-speed of reasoning, in which 27.5% and 16.3% of the children had abnormal results, respectively. A total of 32.5% had abnormal results in the arithmetic tests. Behaviors related to attention deficit/hyperactivity disorder (ADHD) were observed in 48% of the sample. Low score in the Bayley Mental Scale and abnormal result in the Denver test were significantly correlated to ADHD (p = 0.017 and p = 0.004). Abnormal results in the Bayley Mental Scale (p < 0.001), Denver test (p < 0.001) and neurological examination (p = 0.002) were associated with lower IQ.
Conclusions:
The results revealed an increased incidence of behavioral and cognitive disorders at preschool age.
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