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Updated: Jun 26, 2026

In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System
Published on: July 2, 2020
Critical enhancements of MRI contrast and hyperthermic effects by dopant-controlled magnetic nanoparticles
Jung-tak Jang1, Hyunsoo Nah, Jae-Hyun Lee
1Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
Abstract:
Doped up: The incorporation of Zn(2+) dopants in tetrahedral sites leads to the successful magnetism tuning of spinel metal ferrite nanoparticles (see picture). (Zn(0.4)Mn(0.6))Fe(2)O(4) nanoparticles exhibit the highest magnetization value among the metal ferrite nanoparticles. Such high magnetism results in the largest MRI contrast effects (r2=860 mm(-1) s(-1)) reported to date and also huge hyperthermic effects.
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