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Quality-Controlled Sputum Analysis by Flow Cytometry
Published on: August 9, 2021
A chromatic explosion: the development and future of multiparameter flow cytometry
Pratip K Chattopadhyay1, Carl-Magnus Hogerkorp, Mario Roederer
1ImmunoTechnology Section, Laboratory of Immunology, Vaccine Research Center, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-3015, USA. pchattop@mail.nih.gov
Immunology
|January 13, 2009
Summary
Multiparameter flow cytometry now offers detailed immune system study. Advances in hardware, reagents, and analysis reveal new insights into cell biology and immunity.
Area of Science:
- Immunology
- Cell Biology
- Biotechnology
Background:
- Multiparameter flow cytometry (MFC) technology has significantly advanced since the 1990s.
- MFC enables detailed investigation of the immune system.
Purpose of the Study:
- To review the evolution of MFC technology, including hardware, reagents, and data analysis.
- To discuss future advancements and emerging applications of MFC.
- To highlight how MFC reveals novel aspects of cell biology and immunity.
Main Methods:
- Review of historical development and technological advancements in MFC.
- Analysis of current trends in MFC hardware, reagents, and software.
- Exploration of new and emerging applications of MFC in research.
Main Results:
- MFC technology has matured, offering unprecedented detail in immune system analysis.
- Significant progress has been made in MFC hardware, reagents, and data analysis tools.
- New applications are emerging, uncovering previously unknown aspects of cell biology and immunity.
Conclusions:
- MFC is a powerful tool for studying the immune system with increasing sophistication.
- Continued advancements in MFC promise deeper understanding of cellular processes and immune responses.
- The technology is crucial for uncovering novel biological insights and driving innovation in immunology and cell biology.
