[Fibrillary glomerulonephritis]
Related Experiment Video
Updated: Jun 26, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Abstract:
Fibrillary glomerulonephritis is a rare disease of unknown etiology and pathogenesis. In two thirds of cases, it is clinically manifested by the nephrotic syndrome resistant to cytostatic and corticosteroid therapy. Fibrillary glomerulonephritis is diagnosed by electronic microscopy and characterized by the presence of chaotically located fibrils with an average diameter of 18-22 nm in the deposits of immune complexes. Light optical and immunohistochemical studies are of no crucial importance in this disease. Further investigations may answer a number of questions as to the formation of immune complex deposits and ways of their elimination.
Related Concept Videos
Nephrotic Syndrome I : Introduction
Renal Corpuscle
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...
Amyloid Fibrils
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
Amyloid Fibrils
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
Nephrons
Acute Kidney Injury II: Pathophysiology

