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Updated: Jun 26, 2026

Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents
Published on: August 22, 2025
Effect of cannabis usage on the oral environment: a review
P A Versteeg1, D E Slot, U van der Velden
1Department of Periodontology, Academic Centre of Dentistry Amsterdam, Louwesweg 1, Amsterdam, The Netherlands. p.versteeg@acta.nl
Aim:
To evaluate oral environmental changes in cannabis users.
Material And Methods:
The MEDLINE and Cochrane Central register of controlled trails (CENTRAL) were searched up to April 2007 to identify appropriate studies.
Results:
Independent screening of 982 titles and abstracts (MEDLINE-Pubmed) and (Cochrane) papers resulted in seven eligible publications.
Conclusion:
Based on the limited data, it seems justified to conclude that with increasing prevalence of cannabis use, oral health care providers should be aware of cannabis-associated oral side effects, such as xerostemia, leukoedema and an increased prevalence and density of Candida albicans.
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