Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Epigenetic Regulation

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...

Epigenetic Regulation

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.

Epigenetic Regulation

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.

Introduction to Epidemiology

Introduction to Epidemiology

Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...

Genomic Imprinting and Inheritance

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...

Gene-Environment Interactions

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Personality development from early to middle adulthood in the general population and those with mental health difficulties.

Scientific reports·2026

Same author

Associations of perceived family economy, registry-based parental education and income with adolescent psychological distress: the Young-HUNT cross-sectional studies 2006-2008 and 2017-2019.

BMJ open·2026

Same author

To what extent is air pollution associated with cardiorespiratory hospitalisations across Australia? A whole-of-population ecological study.

Public health research & practice·2026

Same author

The association between parent-child and peer relationship quality in adolescence and intimate partner relationship quality in young adulthood: A two-cohort longitudinal investigation.

Journal of research on adolescence : the official journal of the Society for Research on Adolescence·2026

Same author

A Scoping Review of Australian Aboriginal Early Relational Health Knowledge Systems.

Clinical child and family psychology review·2026

Same author

Opportunities to Improve the Implementation of Relational Health Interventions for Children and Families: A Secondary Analysis of a Scoping Review.

Clinical child and family psychology review·2026

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

Methylated DNA Immunoprecipitation

Methylated DNA Immunoprecipitation

Published on: January 2, 2009

Prospects for epigenetic epidemiology.

Debra L Foley¹, Jeffrey M Craig, Ruth Morley

¹Orygen Youth Health Research Centre & Department of Psychiatry, University of Melbourne, Australia.

American Journal of Epidemiology

|January 14, 2009

Summary

This summary is machine-generated.

Epigenetic modifications, like DNA methylation, link environmental factors to gene expression and disease risk. Understanding these epigenetic changes is crucial for developmental epidemiology and aging research.

More Related Videos

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

Published on: February 24, 2015

Methyl-binding DNA capture Sequencing for Patient Tissues

Methyl-binding DNA capture Sequencing for Patient Tissues

Published on: October 31, 2016

Related Experiment Videos

Last Updated: Jun 26, 2026

Methylated DNA Immunoprecipitation

Methylated DNA Immunoprecipitation

Published on: January 2, 2009

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

Published on: February 24, 2015

Methyl-binding DNA capture Sequencing for Patient Tissues

Methyl-binding DNA capture Sequencing for Patient Tissues

Published on: October 31, 2016

Area of Science:

Molecular biology
Genetics
Epidemiology

Background:

Epigenetic modifications mediate environmental influences on gene expression.
Epigenetic analysis can identify joint contributions of genetic and environmental factors to disease risk.
Epigenetic profiles show spatial and temporal variance, relevant to developmental epidemiology and aging.

Purpose of the Study:

To provide a general introduction to epigenetic mechanisms.
To discuss DNA methylation as a key epigenetic mechanism.
To explore factors influencing DNA methylation and its role in development, aging, and disease.

Main Methods:

Review of epigenetic mechanisms, focusing on DNA methylation.
Discussion of genetic and environmental factors affecting DNA methylation.
Overview of methodologies for measuring epigenetic profiles.

Main Results:

Epigenetic mechanisms, particularly DNA methylation, are influenced by genetic and environmental factors.
Epigenetic variations play a role in development, aging, and the onset of common diseases.
Methodological considerations for epidemiological studies incorporating epigenetic analysis are discussed.

Conclusions:

Epigenetic analysis offers insights into gene-environment interactions in disease.
Understanding epigenetic variability is essential for studying development, aging, and disease etiology.
This review highlights the importance of epigenetic mechanisms in understanding complex diseases.