Related Experiment Video
Updated: Jun 26, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Disseminated intravascular coagulation precipitated by thyroid storm.
1Department of Internal Medicine, Wright State University, Good Samaritan Hospital, Dayton, OH 45433, USA. Donald.martin@wpafb.af.mil
Thyroid storm, a rare condition, requires prompt recognition and treatment. This case highlights an atypical presentation of thyroid storm, emphasizing the need to consider unusual symptoms and multi-organ involvement.
Area of Science:
- Endocrinology
- Critical Care Medicine
Background:
- Thyroid storm is a life-threatening endocrine emergency.
- Early diagnosis and management are crucial for patient survival.
Purpose of the Study:
- To report a case of atypical thyroid storm.
- To emphasize the importance of recognizing varied clinical presentations and multi-systemic effects.
Main Methods:
- Case report of a patient with atypical thyroid storm.
- Review of clinical presentation, diagnostic findings, and management.
Main Results:
- The patient presented with normothermic and normotensive thyroid storm.
- Multiple organ dysfunction syndrome, including disseminated intravascular coagulopathy, was observed.
Conclusions:
- Atypical presentations of thyroid storm can occur.
- Clinicians must consider thyroid storm in patients with multi-organ dysfunction, even with non-classical symptoms.
Related Concept Videos
Graves Disease II: Pathophysiology
Graves' Disease I: Introduction
Hyperthyroidism I: Introduction
Hyperthyroidism II: Pathophysiology
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...
Hypothyroidism II: Pathophysiology