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Published on: June 2, 2014
Cardiac cephalgia
Annamaria Bini1, Andrea Evangelista, Paola Castellini
1Department of Neuroscience, Headache Centre, University of Parma, Parma, Italy. bini.annamaria@alice.it
Insights
Cardiac cephalgia, a rare secondary headache, may be the sole indicator of an ischemic cardiovascular event. Diagnosis can be challenging due to variable symptoms and negative initial tests, often requiring coronary angiography.
Area of Science:
- Neurology
- Cardiology
- Emergency Medicine
Background:
- Cardiac cephalgia is classified as a secondary headache (ICD-10 code 10.6) linked to homeostatic disorders.
- It is often an underdiagnosed condition, potentially being the only presenting symptom of an acute coronary event in 27% of cases.
- This headache type typically arises post-exertion and can present with diverse, non-specific clinical features.
Purpose of the Study:
- To critically evaluate the existing medical literature on cardiac cephalgia.
- To highlight the diagnostic challenges and clinical variability associated with this condition.
- To increase awareness of cardiac cephalgia as a potential indicator of ischemic cardiovascular events.
Main Methods:
- Comprehensive review of medical literature concerning cardiac cephalgia.
- Analysis of diagnostic criteria and clinical presentations.
- Examination of cases where headache was the sole manifestation of cardiac events.
Main Results:
- Cardiac cephalgia presents with high variability, mimicking migraine or tension-type headaches.
- Routine cardiac investigations (enzymes, ECG, stress tests) can be negative, necessitating coronary angiography for definitive diagnosis.
- Key indicators for suspicion include older age, no prior headache history, vascular risk factors, and exertional onset.
Conclusions:
- Cardiac cephalgia is a challenging diagnosis due to its mimicry of primary headaches and variable presentation.
- Increased clinical suspicion and awareness are crucial, especially in patients with cardiovascular risk factors presenting with new-onset exertional headaches.
- Further research and recognition are needed to improve the understanding and management of this potentially life-threatening condition.
Abstract:
The purpose of this review was to provide a critical evaluation of medical literature on so-called "cardiac cephalgia" or "cardiac cephalalgia". The 2004 International Classification of Headache Disorders codes cardiac cephalgia to 10.6 in the group of secondary headaches attributed to disorder of homoeostasis. This headache is hardly recognizable and is associated to an ischaemic cardiovascular event, of which it may be the only manifestation in 27% of cases. It usually occurs after exertion. Sometimes routine examinations, cardiac enzymes, ECG and even exercise stress test prove negative. In such cases, only a coronary angiogram can provide sufficient evidence for diagnosis. Cardiac cephalgia manifests itself without a specific pattern of clinical features: indeed, in this headache subtype there is a high variability of clinical manifestations between different patients and also within the same patient. It "mimics" sometimes a form of migraine either accompanied or not by autonomic symptoms, sometimes a form of tension-type headache; on other occasions, it exhibits characteristics that can hardly be interpreted as typical of primary headache. Pain location is highly variable. When the headache occurs as the only manifestation of an acute coronary event, the clues for suspicion are a) older age at onset, b) no past medical history of headache, c) presence of risk factors for vascular disorders and d) onset of headache under stress. Knowledge of cardiac cephalgia is scarce, due to its rare clinical occurrence and to the scant importance given to headache as a symptom concomitantly with an ischaemic cardiac event.
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