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Updated: Jun 26, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Nosocomial infections: epidemiology, pathogenesis, etiology, antibacterial therapy, and prophylaxis]
Abstract:
The review deals with one of the most actual problems of modern medicine, i.e. nosocomial infections. Criteria, epidemiology, pathogenesis and etiology of nosocomial infections are discussed. Up-to-date approaches to prophylaxis and control of nosocomial infections are indicated with special attention to the advantages and disadvantages of some widely used methods. Data on structure of nosocomial infections and their specific features in multipurpose hospitals are indicated. General principles of antimicrobial chemotherapy of nosocomial infections are formulated. The importance on multicentre studies of resistance of hospital pathogens in accordance with internationally recognised methodology is emphasised.
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