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Atrial flutter with spontaneous 1:1 atrioventricular conduction in adults: an uncommon but frequently missed cause
Gioia Turitto1, Philippe Akhrass, Marino Leonardi
1Cardiac Electrophysiology Services, New York Methodist Hospital, Brooklyn, New York 11215, USA. gturitto@aol.com
Insights
Patients with atrial flutter and 1:1 atrioventricular conduction (AVC) exhibit faster AV node conduction, especially with sympathetic stimulation. Awareness of this presentation is crucial to avoid misdiagnosis and mismanagement of atrial flutter.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Arrhythmias
Background:
- Atrial flutter (AFl) with 1:1 atrioventricular conduction (AVC) presents unique challenges in diagnosis and management.
- Understanding the electrophysiological differences between AFl with varying AVC degrees is critical for clinical practice.
Purpose of the Study:
- To compare the clinical and electrophysiological characteristics of patients with AFl and 1:1 AVC versus those with AFl and higher-degree AVC.
- To identify factors contributing to the distinct presentations of AFl with 1:1 AVC.
Main Methods:
- Retrospective comparison of 19 patients with AFl and 1:1 AVC (Group A) against 116 patients with AFl and 2:1 AVC or higher (Group B).
- Analysis included patient demographics, structural heart disease, symptoms, AFl cycle length (CL), and electrophysiological intervals.
Main Results:
- Group A had more patients without structural heart disease (42% vs 17%) and with syncope/presyncope (90% vs 12%).
- AFl CL was longer in Group A (265 ms vs 241 ms).
- Group A demonstrated faster maximal atrial pacing rates with 1:1 AVC and a higher propensity for misdiagnosis as ventricular tachyarrhythmias.
Conclusions:
- The AV node's inherent capacity for faster conduction, particularly with sympathetic stimulation, distinguishes patients with AFl and 1:1 AVC.
- This faster conduction impacts both AVC and AFl CL, necessitating clinical awareness to prevent misdiagnosis and inappropriate treatment.
- Consider AFl with 1:1 AVC in patients presenting with narrow or wide QRS tachycardia exceeding 220 bpm.
Aims:
To compare patients with atrial flutter (AFl) and 1:1 atrioventricular conduction (AVC) with patients with AFl and higher AVC.
Methods:
The characteristics of 19 patients with AFl and 1:1 AVC (group A) were compared with those of 116 consecutive patients with AFl and 2:1 AVC or higher degree AV block (group B).
Results:
Age, gender, and left ventricular function were similar in the two groups. In group A versus group B, more patients had no structural heart disease (42% vs 17%, P < 0.05) and syncope/presyncope (90% vs 12%, P < 0.05). The AFl cycle length (CL) in group A was longer than in group B (265 +/- 24 ms vs 241 +/- 26 ms, P < 0.01). The transition from AFl with 1:1 to 2:1 AVC or vice versa was associated with small but definite changes in AFl CL, which showed larger variations in response to sympathetic stimulation. In group A patients who were studied off drugs, the atrial-His interval was not different from group B, but maximal atrial pacing rate with 1:1 AVC was faster. In group A, five patients were misdiagnosed as ventricular tachyarrhythmias, and three with a defibrillator received inappropriate shocks. Four patients had ablation of AVC and six had ablation of AFl circuit.
Conclusions:
The main difference between groups A and B may be an inherent capacity of the AV node for faster conduction, especially in response to increased sympathetic tone. The latter affects not only AVC but also the AFl CL. One should be aware of the different presentations of AFl with 1:1 AVC to avoid misdiagnosis/mismanagement and to consider the diagnosis in patients with narrow or wide QRS tachycardia and rates above 220/min.
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