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Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy
Published on: July 14, 2023
[Toronto clinical scoring system in diabetic peripheral neuropathy]
Feng Liu1, Ji-Ping Mao, Xiang Yan
1Diabetes Center, Department of Endocrinology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Summary
The Toronto Clinical Scoring System (TCSS) reliably diagnoses diabetic peripheral neuropathy (DPN) with moderate accuracy. Its grading correlates with diabetic nephropathy and retinopathy, showing clinical value.
Area of Science:
- Neurology
- Endocrinology
- Clinical Diagnostics
Background:
- Diabetic peripheral neuropathy (DPN) is a common complication of Type 2 diabetes mellitus (T2DM).
- Accurate diagnostic tools are crucial for managing DPN and its associated microvascular complications.
- The Toronto Clinical Scoring System (TCSS) is a clinical tool for assessing neuropathy.
Purpose of the Study:
- To evaluate the diagnostic value of the Toronto Clinical Scoring System (TCSS) for diabetic peripheral neuropathy (DPN).
- To assess the correlation between TCSS neuropathy grading and the severity of diabetic nephropathy and retinopathy.
Main Methods:
- 209 patients with T2DM underwent TCSS.
- Electrophysiological examination served as the gold standard for DPN diagnosis.
- TCSS scores were compared against electrophysiological results to determine optimal cut-off points.
Main Results:
- A TCSS score of ≥6 demonstrated 76.6% accuracy, 77.2% sensitivity, and 75.6% specificity for DPN diagnosis.
- The Youden index (0.53) and Kappa (0.52) indicated moderate agreement between TCSS and electrophysiological findings.
- A significant positive linear correlation was observed between TCSS neuropathy grading and the severity of diabetic nephropathy and retinopathy (P<0.05).
- Optimal TCSS cut-off points for DPN diagnosis were identified as 5 or 6.
Conclusions:
- The TCSS is a reliable tool for diagnosing DPN in patients with T2DM.
- TCSS neuropathy grading holds significant clinical value, correlating with other diabetic microvascular complications.
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