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Tailoring to RB: tumour suppressor status and therapeutic response

Erik S Knudsen1, Karen E Knudsen

  • 1Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. eknudsen@kimmelcancercenter.org

Nature Reviews. Cancer
|January 15, 2009
PubMed

Insights

The retinoblastoma tumor suppressor (RB) pathway regulates cell division. Its disruption impacts cancer cell growth and predicts patient response to therapies, guiding personalized treatment strategies.

Area of Science:

  • Oncology
  • Molecular Biology
  • Cell Biology

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