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Updated: Jun 26, 2026

Real-time Quaking-induced Conversion Assay for Detection of CWD Prions in Fecal Material
Published on: September 29, 2017
Chronic wasting disease
M Prcina1, J Bardon, E Kontseková
1Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbraska cesta 9, 845 10 Bratislava, Slovak Republic.
Abstract:
Chronic wasting disease (CWD) is the only known prion disease affecting free-ranging animals and has become a serious epidemic in North America. Although any case was reported from Europe, the spread of the disease to other continents and regions cannot be excluded, because the transmission of CWD is the most efficient among prion diseases. This article reviews the host range of CWD including experimentally infected animals, models for potential transmissibility to humans, clinical signs of the disease, pathogenesis, and methods for CWD detection.
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