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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

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Risks for common medical conditions experienced by former preterm infants during toddler years

Jordan S Kase1, Maria Pici, Paul Visintainer

  • 1The Division of Newborn Medicine, The Department of Pediatrics, NYMC, Maria Fareri Children's Hospital at Westchester Medical Center, Valhalla, New York, USA. jordan_kase@nymc.edu

Journal of Perinatal Medicine
|January 16, 2009
PubMed

Insights

Reactive airway disease (RAD), eczema, and gastroesophageal reflux (GERD) are linked in former preterm infants. Newborn respiratory issues predict RAD and GERD, with RAD also associated with eczema.

Area of Science:

  • Neonatal Medicine
  • Pediatric Pulmonology
  • Pediatric Gastroenterology

Background:

  • Reactive airway disease (RAD), eczema, and gastroesophageal reflux (GERD) are common in infants.
  • Understanding associations between these conditions and antenatal/neonatal factors is crucial for early intervention.

Purpose of the Study:

  • To investigate the relationships between RAD, eczema, and GERD.
  • To identify antenatal and neonatal variables associated with these conditions in former preterm infants.

Main Methods:

  • Retrospective observational cohort study of 727 former preterm infants (<2 years old).
  • Analysis of patient demographics, antenatal factors, and comorbidities of prematurity.
  • Correlation of these factors with the incidence of RAD, eczema, and GERD.

Main Results:

  • 12.8% had RAD, 10.5% eczema, and 26.7% GERD.
  • RAD and GERD inversely correlated with gestational age.
  • Newborn respiratory disease predicted RAD and GERD; RAD was associated with eczema.

Conclusions:

  • RAD, eczema, and GERD are strongly associated in former preterm infants.
  • Common underlying factors or exacerbation may explain these associations.
  • Newborn respiratory problems are significant predictors of RAD and GERD.
Abstract

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