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The Drosophila Imaginal Disc Tumor Model: Visualization and Quantification of Gene Expression and Tumor Invasiveness Using Genetic Mosaics
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Genetic analysis of ESCRT function in Drosophila: a tumour model for human Tsg101

Hans-Martin Herz1, Andreas Bergmann

  • 1MD Anderson Cancer Center, Department of Biochemistry and Molecular Biology, Genes and Development Graduate Program, 1515 Holcombe Boulevard, Unit 1000, Houston, TX 77030, USA.

Biochemical Society Transactions
|January 16, 2009
PubMed

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Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...