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Pediatric chronic rhinosinusitis: a retrospective review
Michael W Criddle1, Amy Stinson, Mohammedi Savliwala
1Department of Otolaryngology-Head and Neck Surgery, Wayne State University, 5E-UHC, Detroit, MI 48202, USA. mcriddle@med.wayne.edu
Insights
A stepped treatment protocol using long-term oral antibiotics is effective for pediatric chronic rhinosinusitis (CRS), with 78% achieving resolution. This approach avoids surgery and intravenous antibiotics for most children with CRS.
Area of Science:
- Otolaryngology
- Pediatric Pulmonology
- Allergy and Immunology
Background:
- Pediatric chronic rhinosinusitis (CRS) presents significant morbidity and treatment challenges.
- Current treatments like functional endoscopic sinus surgery (FESS) raise concerns about facial growth interference.
- Alternative stepwise protocols involving maxillary sinus irrigation and intravenous (IV) antibiotics show efficacy but have drawbacks.
Purpose of the Study:
- To review institutional experience in treating medically refractory pediatric CRS.
- To describe the epidemiology of pediatric CRS patients.
- To assess the success of a stepped treatment protocol using long-term oral antibiotics.
Main Methods:
- Retrospective review of medical records for 23 pediatric patients.
- Analysis of treatment outcomes for a stepwise protocol including adenoidectomy, maxillary sinus irrigation, and oral antibiotics.
Main Results:
- Overall clinical resolution was achieved in 96% of patients.
- 78% of patients achieved resolution with oral antibiotics alone, without IV therapy.
- Four patients requiring IV antibiotics were diagnosed with immune deficiency.
- Long-term resolution was 78% overall and 86% for those not requiring IV antibiotics.
- No patients required FESS, and no complications were reported.
Conclusions:
- A stepwise protocol with adenoidectomy, maxillary sinus irrigation, and long-term oral antibiotics is safe and effective for pediatric CRS.
- Patients with underlying immunodeficiency may necessitate long-term IV antibiotic therapy for symptom resolution.
- This protocol offers a viable alternative to FESS for medically refractory pediatric CRS.
Purpose:
Chronic rhinosinusitis (CRS) is a major cause of morbidity in the pediatric population and a difficult entity to treat with a poorly defined pathophysiology and diagnostic criteria. Functional endoscopic sinus surgery (FESS) has proven to be effective for these patients, but concerns remain regarding its possible interference with facial growth. Recently, stepwise treatment protocols, which include maxillary sinus irrigation followed by long-term intravenous (IV) antibiotics, have been demonstrated to be effective alternatives to FESS. However, long-term IV therapy is inconvenient and not without complications. The purpose of this study is to review one institution's experience in treating medically refractory pediatric CRS, specifically to describe the epidemiology of the affected population and estimate the success of a stepped treatment protocol using long-term double oral antibiotic therapy for its treatment.
Materials And Methods:
A retrospective review of the medical records of 23 patients who received treatment.
Results:
Mean age was 2.3 years. Clinical resolution was achieved in 96% of patients and in 78% without the use of IV antibiotics. Four patients who required IV antibiotics subsequently tested positive for immune deficiency. Long-term resolution rate was 78% overall and 86% for those that did not require IV antibiotics. No complications were reported, and no patients required FESS.
Conclusions:
A stepwise protocol that includes concurrent adenoidectomy and bilateral maxillary sinus irrigation followed by long-term double oral antibiotic therapy is safe and effective for the treatment of pediatric CRS. Patients with immunodeficiency may require long-term IV therapy to achieve symptom resolution.
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