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Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
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IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
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Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
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Published on: October 14, 2016

Changing axis deviation during acute myocardial infarction.

Salvatore Patanè, Filippo Marte

    International Journal of Cardiology
    |January 16, 2009
    PubMed
    Summary
    This summary is machine-generated.

    This study reports a rare case of changing axis deviation during acute myocardial infarction in an elderly man. The findings highlight a transient left posterior hemiblock pattern associated with significant coronary artery obstruction.

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    Area of Science:

    • Cardiology
    • Electrocardiography
    • Myocardial Infarction

    Background:

    • Changing axis deviation is an uncommon finding during acute myocardial infarction.
    • Atrial fibrillation is frequently associated with axis deviation during myocardial infarction.
    • Left posterior hemiblock is a rare electrocardiographic finding.

    Observation:

    • A 70-year-old Italian man presented with acute myocardial infarction.
    • The patient exhibited transient right axis deviation with a left posterior hemiblock pattern.

    Findings:

    • The observed axis deviation was linked to significant right coronary artery obstruction.
    • Collateral circulation between the left coronary system and the posterior descending artery was implicated.

    Implications:

    • This case underscores the importance of recognizing rare electrocardiographic patterns in acute myocardial infarction.
    • Understanding axis deviation changes can aid in diagnosing coronary artery obstruction and assessing collateral flow.
    • Further research into the mechanisms of transient hemiblocks during myocardial infarction is warranted.