Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A system for compartmental modelling and simulation.

M S Leaning1, M A Boroujerdi

  • 1Department of Statistical Science, University College London, U.K.

Computer Methods and Programs in Biomedicine
|June 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A negative feedback model for a mechanism based description of longitudinal observations. Application for bone turnover biomarkers.

Methods of information in medicine·2013
Same author

High concordance between expert anaesthetists' actions and advice of decision support system in achieving oxygen delivery targets in high-risk surgery patients.

British journal of anaesthesia·2012
Same author

Introduction of a new incentive and target-based contract for family physicians in the UK: good for older patients with diabetes but less good for women?

Diabetic medicine : a journal of the British Diabetic Association·2008
Same author

Gender differences in growth hormone response to exercise before and after rhGH administration and the effect of rhGH on the hormone profile of fit normal adults.

Clinical endocrinology·2005
Same author

The growth hormone/insulin-like growth factor-I axis hormones and bone markers in elite athletes in response to a maximum exercise test.

The Journal of clinical endocrinology and metabolism·2003
Same author

The effect of four weeks of supraphysiological growth hormone administration on the insulin-like growth factor axis in women and men. GH-2000 Study Group.

The Journal of clinical endocrinology and metabolism·2000
Same journal

Accounting for approximation errors using surrogate-based parameter estimation of cardiac mechanics digital twins.

Computer methods and programs in biomedicine·2026
Same journal

Facial iPPG heatmap patterns based on period-aware autoencoder show association with carotid atherosclerosis towards non-contact hemodynamic assessment.

Computer methods and programs in biomedicine·2026
Same journal

Explainable machine learning models predict liver fibrosis risk and outcome in the general population: Development and multi-cohort external validation.

Computer methods and programs in biomedicine·2026
Same journal

Evaluation of surrogate endpoints for survival outcomes using the surrogate package in R.

Computer methods and programs in biomedicine·2026
Same journal

Relative spectral and frication-based descriptors as numerical indicators of place of articulation shifts in fricatives produced by Polish children.

Computer methods and programs in biomedicine·2026
Same journal

Leaflet resection improves valve expansion and hemodynamic performance in redo TAVI with balloon- and self-expanding transcatheter heart valve configurations.

Computer methods and programs in biomedicine·2026
See all related articles

This study introduces versatile software for modeling compartmental systems, enabling rapid development. Its application in insulin planning for diabetic patients demonstrates the software

Area of Science:

  • Computational biology
  • Systems biology
  • Mathematical modeling

Background:

  • Compartmental systems are widely used to model biological and chemical processes.
  • Existing modeling approaches can be complex and time-consuming for rapid development.
  • There is a need for versatile software to facilitate the creation and simulation of compartmental models.

Purpose of the Study:

  • To describe a novel software package for the modeling and simulation of compartmental systems.
  • To provide a versatile tool for rapid model development and analysis.
  • To demonstrate the software's utility through classical examples and a practical application.

Main Methods:

  • The software is based on a generalization of compartmental system equations.

Related Experiment Videos

  • It is implemented in Pascal for IBM PC and compatible computers.
  • Model development is illustrated with simple examples and a complex case study.

    • Main Results:

    • The software package allows for the creation and simulation of compartmental models.
    • Classical examples demonstrate the software's functionality and ease of use.
    • A model-based system for insulin planning in diabetic patients was successfully developed.

    Conclusions:

    • The developed software offers a versatile and efficient approach to compartmental system modeling.
    • The methodology and software are powerful tools for both basic research and applied problems.
    • The application in insulin planning highlights the potential for clinical decision support systems.