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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
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Prenatal hyperhomocysteinemia as a model of oxidative stress of the brain

A V Makhro1, A P Mashkina, O A Solenaya

  • 1M. V. Lomonosov Moscow State University, Moscow, Russia.

Bulletin of Experimental Biology and Medicine
|January 16, 2009
PubMed

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Hepatic Encephalopathy01:29

Hepatic Encephalopathy

DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...