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Updated: Jun 26, 2026
Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
Sinus grafting using autogenous bone and platelet-rich plasma: histologic outcomes in humans
Mario Aimetti1, Federica Romano, Claudia Dellavia
1Department of Biomedical Sciences and Human Oncology, Section of Periodontology, University of Torino, Torino, Italy. mario.aimetti@unito.it
Abstract:
Four partially edentulous patients received particulate autogenous bone and platelet-rich plasma (PRP) in one sinus and particulate autogenous bone alone in the contralateral sinus. After 6 months of healing, two or three Osseotite implants were inserted, and an additional Osseotite mini-implant was placed into the graft through the lateral wall of the sinus. At abutment connection, the mini-implants were retrieved for histologic examination. Despite similar clinical and radiographic healing patterns, a higher bone-to-implant contact rate was observed on the implants placed in bone and PRP than on those placed in bone only (46.75% +/- 13.6% versus 20.5% +/- 5.57%, respectively).
