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Updated: Jun 26, 2026

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer
Published on: March 17, 2016
A systems approach to analysis of molecular complexity in breast cancer
Bryan T Hennessy1, Ana Maria Gonzalez-Angulo, Mark S Carey
1Department of Systems Biology and the Kleberg Center for Molecular Markers, M. D. Anderson Cancer Center, Houston, Texas 77030, USA. bhennessy@mdanderson.org
Abstract:
In this issue of Clinical Cancer Research, Andre et al. apply high-resolution arrays to elucidate copy number anomalies in breast cancer. They identify distinct copy number anomaly patterns in different breast cancer subtypes that implicate a number of genes as potential therapeutic targets and as potential markers of therapy responsiveness.
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