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[A primary report on thrombolytic therapy of acute myocardial infarction in 40 cases]
D Hu1
1First Hospital, Beijing Medical University.
Insights
This study compared thrombolytic agents for acute myocardial infarction, finding intracoronary thrombolysis most effective for reperfusion. Intravenous streptokinase showed higher reperfusion rates than urokinase, with minimal bleeding complications.
Area of Science:
- Cardiology
- Internal Medicine
Abstract:
Forty cases with acute myocardial infarction were treated by thrombolysis from June, 1989 through September, 1990. 32 males and 8 females. Age 44-76 (60 +/- 7.1) years. Coronary angiography was performed in 19 patients 10 days after intravenous thrombolysis on average. With intravenous thrombolysis the reperfusion rates were 69.2% (9/13) for streptokinase and 53.8% (7/13) for urokinase (Green Cross Company, Japan) according to the clinical criteria. No reperfusion was observed in 8 cases treated by China-made urokinase. The reperfusion rate of intracoronary thrombolysis was 85.7% (6/7). 5 cases had hemorrhagic complications, skin ecchymosis in 2 and mild gastrointestinal bleeding in 3, and no transfusion was necessary. No intracranial hemorrhage was noticed.