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Updated: Jun 26, 2026
11:56
Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
Published on: August 24, 2015
Acquired epidermodysplasia verruciformis.
Heather D Rogers1, Jennifer L Macgregor, Kristin M Nord
1Department of Dermatology, Columbia University Medical Center, New York, New York, USA. hr2121@columbia.edu
Journal of the American Academy of Dermatology
|January 20, 2009
Summary
Epidermodysplasia verruciformis (EV) is a rare genetic skin disorder. Acquired EV-like syndromes in immunocompromised individuals, including HIV patients, present unique challenges and limited treatment options.
Area of Science:
- Dermatology
- Virology
- Immunology
Background:
- Epidermodysplasia verruciformis (EV) is a rare genodermatosis linked to specific human papillomavirus (HPV) types.
- It typically manifests in childhood with tinea versicolor-like macules that can progress to squamous cell carcinoma.
Observation:
- An EV-like syndrome has been observed in individuals with compromised cell-mediated immunity.
- This report details two HIV-positive patients with an EV-like syndrome.
Findings:
- The study reviews existing literature on EV in immunocompromised patients.
- The term "acquired epidermodysplasia verruciformis" is proposed for EV in this population.
Implications:
- This condition highlights the link between immune status and HPV susceptibility.
- Further research is needed to explore effective treatment strategies for acquired EV.
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