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Related Experiment Video

Updated: Jun 26, 2026

A Simple Method of Mouse Lung Intubation
07:06

A Simple Method of Mouse Lung Intubation

Published on: March 21, 2013

An improved simple method of mouse lung intubation.

Kelvin D MacDonald1, Herng-Yu Sucie Chang, Wayne Mitzner

  • 1Dept of Environmental Health Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|January 20, 2009
PubMed
Summary

Repeated intubation in mice simplifies studying lung disease, enabling longitudinal research. This technique enhances statistical power by using each mouse as its own control.

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Area of Science:

  • Pulmonary Medicine
  • Animal Models
  • Respiratory Research

Background:

  • Mice are commonly used to model human lung diseases.
  • Repeated intubation is underutilized for longitudinal studies in mice.
  • Existing intubation methods can be technically challenging.

Purpose of the Study:

  • To present a simplified, cost-effective procedure for repeated tracheal intubation in mice.
  • To facilitate routine intubation for longitudinal studies of lung disease in individual mice.
  • To enhance the statistical power of mouse-based lung disease research.

Main Methods:

  • Detailed description of a novel, simplified intubation technique.
  • Emphasis on ease of training, low cost, and minimal expertise required.

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An Improved Method for Rapid Intubation of the Trachea in Mice

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Related Experiment Videos

Last Updated: Jun 26, 2026

A Simple Method of Mouse Lung Intubation
07:06

A Simple Method of Mouse Lung Intubation

Published on: March 21, 2013

Improved Methodology for Liquid Delivery to the Mouse Lung: Intubation using a Consumer Otoscope
13:50

Improved Methodology for Liquid Delivery to the Mouse Lung: Intubation using a Consumer Otoscope

Published on: June 17, 2025

An Improved Method for Rapid Intubation of the Trachea in Mice
08:46

An Improved Method for Rapid Intubation of the Trachea in Mice

Published on: February 22, 2016

  • Procedure designed for routine application in laboratory settings.

    • Main Results:

    • The described method simplifies repeated intubation in mice.
    • The technique is accessible with minimal training, expense, and expertise.
    • Enables longitudinal data collection from individual animals.

    Conclusions:

    • This simplified intubation protocol can be widely adopted by research laboratories.
    • Facilitates longitudinal studies, improving the understanding of lung disease progression.
    • Increases statistical power by enabling within-subject comparisons.