Related Experiment Video
Updated: Aug 19, 2026

3D Printing of Biomolecular Models for Research and Pedagogy
Published on: March 13, 2017
Modelling protein three-dimensional structure using tritium planigraphy
A Gedrovich1, A Shishkov, V Goldanskii
1N.N. Semenov Institute of Chemical Physics, Academy of Sciences, Moscow, USSR.
Abstract:
We propose the use of data on the topography of the label-accessible surface of a protein molecule obtained by the method of tritium planigraphy as a criterion for choosing the optimal intermediate arrangements of alpha-helices in globular proteins so as to model their three-dimensional structures. This approach has been used for modelling the three-dimensional structure of parvalbumin III from pike. The proposed model has been compared with high-resolution X-ray structural data for a related protein, paryvalbumin from carp. The possibilities and limitations of this approach are discussed.
More Related Videos
08:27Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy
Published on: January 7, 2019
10:10Neutron Crystallography Data Collection and Processing for Modelling Hydrogen Atoms in Protein Structures
Published on: December 1, 2020
Related Concept Videos
Molecular Models
Newman Projections
The organic molecules rotate across the single bonds leading to numerous temporary three-dimensional structures of varying energy known as conformers.
Protein Organization
The primary structure of a protein is its amino acid sequence.
Electron Microscope Tomography and Single-particle Reconstruction
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...