Related Experiment Video
Updated: Jun 26, 2026
A Periprosthetic Joint Candida albicans Infection Model in Mouse
Published on: February 2, 2024
No evidence to link prosthetic joint infections with dental procedures
Jennifer Rodgers1, Derek Richards
1Department of Public Health, NHS Forth Valley, Carseview House, Castle Business Park, Stirling, Scotland, UK.
Data Sources:
Medline and bibliographies of relevant papers were used to source relevant studies. Case reports and references to relevant conference presentations were also included. Animal and in-vitro studies were excluded. Publications in English, French and German were included.
Study Selection:
All relevant articles including case studies and references to abstracts of conference presentations were considered.
Data Extraction And Synthesis:
A qualitative summary was made of relevant data.
Results:
Of 144 articles retrieved, there were 23 prospective studies but no randomised or comparative trials. Twenty-seven reports (18.8%) favoured prophylaxis for special circumstances, 11 publications (7.6%) did not perceive any benefit and 106 (73.6%) took no clear position.
Conclusions:
Infections of total hip or knee replacements because of haematogenous seeding following dental intervention are very rare. The scientific rationale for systemic or local antimicrobial prophylaxis is very weak at best.
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