Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Confocal Fluorescence Microscopy

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Intra- and inter-day effects of novel robot-assisted hand movement training in individuals with post-stroke hemiparesis: a single-arm pilot study.

Fujita medical journal·2026

Same author

Erratum: Nonlinear dynamics of a self-mixing thin-slice solid-state laser subjected to Doppler-shifted optical feedback [Phys. Rev. E 104, 044203 (2021)].

Physical review. E·2023

Same author

[Steroid resistance of severe asthma - mechanisms and therapeutic targets].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica·2022

Same author

[Usefulness of an anti-mouse cerebellar tissue-derived antigen antibody test in predicting immunotherapy efficacy in patients with idiopathic cerebellar ataxia].

Rinsho shinkeigaku = Clinical neurology·2022

Same author

Erratum: Nonlinear dynamics of a self-mixing thin-slice solid-state laser subjected to Doppler-shifted optical feedback [Phys. Rev. E 104, 044203 (2021)].

Physical review. E·2022

Same author

Nonlinear dynamics of a self-mixing thin-slice solid-state laser subjected to Doppler-shifted optical feedback.

Physical review. E·2021

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Published on: February 4, 2017

Three-channel three-dimensional self-mixing thin-slice solid-state laser-Doppler measurements.

Takayuki Ohtomo¹, Seiichi Sudo, Kenju Otsuka

¹Department of Human and Information Science, Tokai University, Hiratsuka, Kanagawa 259-1292, Japan.

|January 20, 2009

Summary

This study presents a novel three-channel laser-Doppler system for highly sensitive, real-time measurements. The system enables simultaneous tracking of multiple nanometer vibrations and particle movements.

More Related Videos

Experimental Investigation of the Flow Structure over a Delta Wing Via Flow Visualization Methods

Experimental Investigation of the Flow Structure over a Delta Wing Via Flow Visualization Methods

Published on: April 23, 2018

High-speed Particle Image Velocimetry Near Surfaces

High-speed Particle Image Velocimetry Near Surfaces

Published on: June 24, 2013

Related Experiment Videos

Last Updated: Jun 26, 2026

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Published on: February 4, 2017

Experimental Investigation of the Flow Structure over a Delta Wing Via Flow Visualization Methods

Experimental Investigation of the Flow Structure over a Delta Wing Via Flow Visualization Methods

Published on: April 23, 2018

High-speed Particle Image Velocimetry Near Surfaces

High-speed Particle Image Velocimetry Near Surfaces

Published on: June 24, 2013

Area of Science:

Optics
Photonics
Laser Physics

Background:

Laser-Doppler velocimetry (LDV) is a non-contact optical technique for measuring velocity.
Traditional LDV systems often face limitations in multi-target tracking and sensitivity.
Advancements are needed for precise measurements of micro/nanoscale dynamics.

Purpose of the Study:

To develop a real-time, three-channel self-mixing laser-Doppler system with enhanced optical sensitivity.
To demonstrate the capability for simultaneous measurement of multiple targets and particle dynamics.
To enable precise velocity vector identification of micro-particles.

Main Methods:

Utilized a laser-diode-pumped thin-slice Nd:GdVO(4) laser.
Employed a carrier-frequency-division-multiplexing scheme with three pairs of acoustic optical modulators (frequency shifters).
Implemented a three-channel FM-wave demodulation circuit for signal processing.

Main Results:

Achieved successful real-time, three-channel self-mixing laser-Doppler measurements.
Demonstrated simultaneous independent measurement of three different nanometer-vibrating targets.
Showcased simultaneous measurement of small particles in Brownian motion from three directions.
Successfully identified the velocity vector of small particles in a flowing fluid.

Conclusions:

The developed system offers extreme optical sensitivity for laser-Doppler measurements.
The three-channel multiplexing scheme enables simultaneous and independent tracking of multiple targets.
This technique is effective for characterizing micro/nanoscale particle dynamics and fluid flow velocity vectors.