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Updated: Jun 26, 2026

Assessment of Human Adipose Tissue Microvascular Function Using Videomicroscopy
Published on: September 29, 2017
Obesity and vascular risk
1Center for Molecular and Vascular Biology, KU Leuven, Campus Gasthuisberg, 3000 Leuven, Belgium. roger.lijnen@med.kuleuven.be
Abstract:
Obesity is a common disorder and a known risk factor for vascular thrombotic complications. Development of obesity is associated with extensive modifications in adipose tissue involving adipogenesis, angiogenesis and extracellular matrix proteolysis. Studies using a nutritionally induced obesity model in transgenic mice support a role of the fibrinolytic (plasminogen/plasmin) and matrix metalloproteinase (MMP) systems in these processes. Venous or arterial thrombosis models in obese mice confirm a prothrombotic risk associated with obesity.
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