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Related Experiment Video

Updated: Jun 26, 2026

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
11:35

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function

Published on: December 8, 2010

Cutaneous bioengineering instrumentation standardization: the Tissue Viability Imager.

Gert E Nilsson1, Hongbo Zhai, Heidi P Chan

  • 1Department of Biomedical Engineering, Linköping University, Linköping, Sweden. gerni@glocalnet.net

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [And] International Society for Digital Imaging of Skin (ISDIS) [And] International Society for Skin Imaging (ISSI)
|January 21, 2009
PubMed
Summary

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Tissue Viability Imaging (TiVi) shows stable performance for mapping skin red blood cell concentration. This bioengineering technology is reliable for clinical and laboratory use, with minimal variation and drift.

Area of Science:

  • Bioengineering
  • Biomedical Imaging
  • Dermatology

Background:

  • Tissue Viability Imaging (TiVi) is a novel bioengineering technology for remote 2D mapping of skin red blood cell concentration (RBC(conc)).
  • Evaluation of critical performance parameters is essential before TiVi deployment in laboratory, work-site, and clinical settings.

Purpose of the Study:

  • To assess the performance of a production batch of Tissue Viability Imagers.
  • Key parameters evaluated include short- and long-term stability, image uniformity, and sensitivity to distance, image size, ambient light, and object curvature.

Main Methods:

  • Four TiVi devices from a single production batch were tested.
  • Performance was evaluated in both industrial and dermatological laboratory environments.

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Related Experiment Videos

Last Updated: Jun 26, 2026

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
11:35

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function

Published on: December 8, 2010

Fabrication and Characterization of a Conformal Skin-like Electronic System for Quantitative, Cutaneous Wound Management
08:50

Fabrication and Characterization of a Conformal Skin-like Electronic System for Quantitative, Cutaneous Wound Management

Published on: September 2, 2015

Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding
08:35

Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding

Published on: February 26, 2015

Main Results:

  • Systematic sensitivity drift was minimal (<1.02% over time).
  • Inter-unit sensitivity differences were limited to 4.1%, primarily due to offset.
  • Image uniformity variations were below 3.08% (corners) and 1.93% (center), reducible with normalization.
  • Ambient light caused ~10% reduction in readings; distance and image size had no effect.
  • Curved surfaces showed <10% edge effect.

Conclusions:

  • Critical performance parameters of TiVi devices are stable for monitoring skin RBC(conc) variations.
  • A two-point calibration method can enhance inter-laboratory comparability by minimizing sensitivity differences.