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Related Experiment Video

Updated: Jun 26, 2026

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Published on: May 12, 2011

Charles Bonnet syndrome.

Simona Cammaroto¹, Giangaetano D'Aleo, Chiara Smorto

¹IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.

Functional Neurology

|January 21, 2009

Summary

Charles Bonnet syndrome (CBS) causes visual hallucinations in older adults with vision loss. This review discusses CBS causes, mechanisms, and treatments, noting its increasing incidence due to population aging.

Area of Science:

Neurology
Ophthalmology
Geriatrics

Background:

Charles Bonnet syndrome (CBS) is characterized by visual hallucinations in individuals with visual impairment.
It often affects older patients experiencing deafferentation of the visual cortex.

Purpose of the Study:

To review the existing literature on Charles Bonnet syndrome.
To discuss the aetiologies, pathophysiology, and treatment options for CBS.

Main Methods:

Literature review of scientific papers and case studies related to Charles Bonnet syndrome.

Main Results:

The review covers the underlying causes and biological mechanisms of CBS.
Current treatment strategies for managing visual hallucinations in CBS are discussed.

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Conclusions:

The incidence of Charles Bonnet syndrome is likely increasing.
Population aging and the rise in associated vision and cerebral disorders contribute to the growing prevalence of CBS.