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Updated: Jun 26, 2026
06:53
Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
Published on: November 11, 2016
Circadian clock genes in reproductive tissues and the developing conceptus
Hamid Dolatshad1, Fred C Davis, Martin H Johnson
1Department of Biology, Northeastern University, Boston, MA 02115, USA. hd241@cantab.net
Reproduction, Fertility, and Development
|January 21, 2009
Summary
The body
Area of Science:
- Chronobiology
- Reproductive Biology
- Genetics
Background:
- The circadian clock regulates physiological processes via gene expression rhythms.
- Circadian clock genes are found in central and peripheral tissues, including reproductive organs and the conceptus.
- Environmental and genetic factors influencing the circadian clock impact reproduction and development.
Purpose of the Study:
- To investigate the presence and role of circadian clock gene expression in human reproduction.
- To determine if circadian rhythms are present in male reproductive tissues and the conceptus.
- To explore the influence of circadian rhythms on reproductive function and early development.
Main Methods:
- Review of existing genetic and molecular biology studies on circadian clock gene expression.
- Analysis of published data on circadian rhythmicity in female and male reproductive tissues.
- Examination of studies on the conceptus and its circadian gene expression patterns.
Main Results:
- Circadian clock genes are expressed in all studied female and male reproductive tissues and the conceptus.
- A robust circadian rhythm is evident in female reproductive tissues.
- Circadian rhythmicity in male reproductive tissues and the conceptus requires further investigation.
Conclusions:
- The circadian clock plays a significant role in reproductive function and potentially early development.
- Further research is needed to confirm circadian rhythmicity in male reproductive tissues and the conceptus.
- Understanding circadian clock mechanisms in reproduction is crucial for fertility and developmental studies.
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