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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
Biosynthetic studies of spiroleptosphol
Takanori Murakami1, Noboru Takada, Masaru Hashimoto
1Faculty of Agriculture and Life Science, Hirosaki University, 3-Bunkyo-cho, Hirosaki 036-8561, Japan.
Abstract:
Studies of the biosynthesis of spiroleptosphol (1) revealed that 1 comprised a heptaketide (C1, C5-C10, and C12-C18 moiety), two methyl carbons (C19 and C20) from methionine, and a C(3) unit (C3, C4, and C11 moiety) derived through the TCA cycle.
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