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Evaluation of the management of heart failure in primary care
Melanie J Calvert1, Aparna Shankar, Richard J McManus
1Department of Primary Care and General Practice, University of Birmingham, Edgbaston, Birmingham, UK. m.calvert@bham.ac.uk
Insights
Most heart failure patients in UK primary care receive ACE inhibitors/ARBs, but few reach target doses. Beta-blocker use is low, with younger males receiving optimal treatment. New strategies are needed for equitable care.
Area of Science:
- Cardiology
- Primary Care Research
- Pharmacotherapy
Background:
- Guideline adherence for heart failure treatment in UK primary care is not well understood.
- Current practices may not align with established European Society of Cardiology (ESC) guidelines.
Purpose of the Study:
- To determine the prevalence of heart failure in a large UK primary care population.
- To assess the pharmacological management of heart failure against ESC and NICE guidelines.
Main Methods:
- A retrospective cohort study analyzed routinely collected data from 163 UK general practices.
- Data spanned a 5-year period up to December 31, 2006, from the DIN-LINK database.
- Nearly 1.43 million patients were screened to identify heart failure cases.
Main Results:
- An estimated 0.7% prevalence of heart failure (9311 patients) was identified, with a mean age of 78 years.
- While 79.6% received loop diuretics and 71.1% received ACE inhibitors/ARBs, only 36.6% were prescribed beta-blockers.
- Combination therapy (ACE inhibitor/ARB and beta-blocker) was used in only 29.3% of patients, with low rates of guideline target dose achievement for ACE inhibitors (35%) and beta-blockers (11.5%).
Conclusions:
- Most heart failure patients receive ACE inhibitors/ARBs, but optimal titration to guideline-recommended doses is infrequent.
- Beta-blocker prescription rates are suboptimal, indicating a gap in guideline implementation.
- Younger males with heart failure appear more likely to receive maximal therapy, highlighting potential inequities in treatment that require new strategies for universal optimal care.
Background:
The extent to which guidelines for the treatment of heart failure are currently followed in primary care in the UK is unclear.
Objective:
To evaluate the prevalence of heart failure and the pharmacological management of heart failure in relation to European Society of Cardiology (ESC) and National Institute for Health and Clinical Excellence guidelines.
Methods:
Retrospective cohort study using routinely collected data from 163 general practices across Great Britain contributing data to the Doctors Independent Network (DIN-LINK) database over a 5-year period until December 31, 2006.
Results:
From a patient population of nearly 1.43 million, 9311 patients with heart failure were identified [mean age 78 years (SD 12)], giving an estimated prevalence of 0.7%. Of these, 7410 (79.6%) were prescribed a loop diuretic, 6620 (71.1%) were prescribed an angiotensin-converting enzyme (ACE) inhibitor or ARB, 3403 (36.6%) were prescribed beta-blockers but only 2732 (29.3%) were prescribed an ACE inhibitor or ARB and a beta-blocker in combination. Thirty-five per cent of patients prescribed ACE inhibitor and 11.5% of those prescribed beta-blockers met ESC guideline target doses. Age, gender and comorbidity predicted whether patients received beta-blocker or ACE inhibitor with younger males being more likely to receive maximal therapy.
Conclusions:
These data suggest that while most patients with heart failure receive an ACE inhibitor/ARB in primary care, few are titrated to target dose and many do not receive a beta-blocker. Optimum treatment appears to be most likely for young men. New strategies are required to ensure equitable and optimal treatment for all.
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