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Ti(III)-promoted radical cyclization of epoxy enones. Total synthesis of (+)-paeonisuffrone

María Martín-Rodríguez1, Raquel Galán-Fernández, Andrés Marcos-Escribano

  • 1Departamento de Química Orgánica, Universidad de Salamanca, 37008 Salamanca, Spain.

The Journal of Organic Chemistry
|January 22, 2009
PubMed

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Overview
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Epoxidation of alkenes via oxidation with peroxy acids involves the conversion of a carbon–carbon double bond to an epoxide using the oxidizing agent meta-chloroperoxybenzoic acid, commonly known as MCPBA. Since the O–O bond of peroxy acids is very weak, the addition of electrophilic oxygen of peroxy acids to...
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