Related Experiment Video
Updated: Jun 26, 2026

10:31
Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
Developmental pathways in food allergy: a new theoretical framework
A DunnGalvin1, A Gaffney, J O'B Hourihane
1University College Cork, Ireland.
Allergy
|January 22, 2009
Summary
Food allergy (FA) significantly impacts children's psychological development. This study introduces a novel developmental framework to understand and manage FA's psychosocial effects on children.
Area of Science:
- Pediatric Psychology
- Developmental Psychology
- Food Allergy Research
Background:
- No existing model addresses psychosocial development in pediatric food allergy (FA).
- This gap hinders effective prediction and management of FA's impact on children.
- Implications for prevention, treatment, intervention, and health policy are limited.
Purpose of the Study:
- To establish an integrated conceptual framework for FA-related psychosocial development.
- To explain the onset, progression, and maintenance of cognitions, emotions, and behaviors in children with FA.
- To specifically address critical developmental transition points.
Main Methods:
- Conducted 15 focus groups with 62 children aged 6-15 years.
- Employed developmentally appropriate techniques to encourage discussion and engagement.
- Utilized grounded theory for data analysis.
Main Results:
- Food allergy impacts children's psychological development in age- and disease-specific ways.
- Six key themes emerged: meanings of food, autonomy/control/self-efficacy, peer relationships, risk/safety, self/identity, and coping strategies.
- Coping is an interactive, cumulative process influenced by age, gender, and disease specifics.
Conclusions:
- A child's coping with FA is a developmental process, not just a strategy.
- Integrating an FA-specific developmental framework into treatment is crucial for effective care.
- This framework aids in managing the transition from pediatric to adult healthcare.
Related Concept Videos
Allergic Reactions
Overview
Allergic Reactions: Anaphylaxis
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Taste Buds and Receptors
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
Drug Toxicity: Allergic Reactions
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Asthma: Pathogenesis and Management
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Allergic Drug Reactions
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...

