[A medical and economic study about use of hemostatic glues in cardiac surgery]
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Sandra Ameslant1, Capuccine Delgove, Blaise Tramier
1Pharmacie du Groupe Hospitalier Sud, CHU Amiens, Salouel, France. sandra.ameslant@free.fr
Insights
In cardiac surgery, biological and synthetic glues did not reduce bleeding and increased hospital costs. This study found glues led to more transfusions and longer intensive care unit stays.
Area of Science:
- Cardiovascular Surgery
- Medical Devices
- Health Economics
Context:
- Cardiac surgery involves procedures like valvular replacement and coronary artery bypass grafting.
- The use of biological and synthetic glues as adjuncts in cardiac surgery is common.
- Assessing the economic and medical impact of these glues is crucial for clinical practice guidelines.
Purpose:
- To evaluate the medical and economic impact of using biological and synthetic glues in cardiac surgery.
- To compare outcomes between patients treated with glues and those not treated.
- To inform hospital drug commission guidelines.
Summary:
- A 3-month prospective observational study included 154 cardiac surgery patients.
- Fifty-seven patients received glues; indications included valvular replacement (48%) and CABG (37%).
- Glue use was associated with significantly higher blood transfusion requirements and longer ICU stays (p<0.05).
Impact:
- The use of glues in cardiac surgery did not decrease post-operative bleeding.
- Glues significantly increased the overall cost of hospital stay.
- Findings led to validated hospital guidelines regarding glue usage.
Introduction:
The impact of the use of biological and synthetic glues in cardiac surgery was assessed by an economic and medical study.
Material And Methods:
The observational prospective study had duration of three months. All the patients undergoing cardiac surgery were included in the study. The end points were medical (blood transfusion) and economic (duration and cost of the stay in hospital). There were 2 groups: treated or not by glues.
Statistical Analysis:
T Student tests.
Results:
Among 154 patients, the 2 principal indications were valvular replacement (48%) and coronary artery bypass grafting (37%). Fifty seven (37%) patients received a glue. The number of transfused globular units and the duration of the stay in the intensive care unit were significantly higher (p<0.05) by treated patients.
Conclusion:
Not only the use of glues did not decrease the post-operative bleedings but it increased also the cost of the stay in hospital. Guidelines were validated by the hospital Commission on drugs.
