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Outcomes of surgical intervention for isolated active mitral valve endocarditis

Amir M Sheikh1, Abdelsalam M Elhenawy, Manjula Maganti

  • 1Peter Munk Cardiac Centre, Toronto General Hospital, Toronto, Ontario, Canada.

The Journal of Thoracic and Cardiovascular Surgery
|January 22, 2009
PubMed
Abstract

Insights

Surgical intervention for active mitral valve endocarditis has high long-term morbidity and mortality. Event-free survival is worse for patients with nonnative valves compared to native valves.

Area of Science:

  • Cardiovascular Surgery
  • Infectious Diseases
  • Cardiac Valve Surgery

Background:

  • Infective endocarditis affecting the mitral valve is a serious condition.
  • Long-term outcomes of surgical intervention for isolated active mitral valve endocarditis are not well-documented.

Purpose of the Study:

  • To evaluate the long-term outcomes of surgical intervention for active infective endocarditis confined to the mitral valve.

Main Methods:

  • A 27-year retrospective study of 104 patients with active mitral valve endocarditis.
  • Surgical interventions included valve repair or replacement, with radical resection and reconstruction for annular abscesses.
  • Mean follow-up was 5.6 years, with complete follow-up data.

Main Results:

  • Overall survival at 10 years was 58%.
  • Freedom from recurrent endocarditis and reoperation at 7 years was 89% and 94%, respectively.
  • Event-free survival was significantly lower in patients with nonnative valves (prosthetic or previously repaired) compared to native valves.

Conclusions:

  • Surgical treatment for isolated active mitral valve endocarditis is associated with significant long-term morbidity and mortality.
  • Patients with nonnative mitral valve endocarditis experience worse event-free survival.

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