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Morphologic features of atrioventricular septal defect with only ventricular component: further observations

Iki Adachi1, Hideki Uemura, Karen P McCarthy

  • 1Cardiac Morphology Unit, Imperial College London, National Heart & Lung Institute, London, United Kingdom.

The Journal of Thoracic and Cardiovascular Surgery
|January 22, 2009
PubMed

Insights

Atrioventricular septal defect with only a ventricular component is the mildest form, characterized by less severe heart deformities. Upwardly displaced valve leaflets may increase the risk of late valve dysfunction after surgery.

Area of Science:

  • Cardiovascular Pathology
  • Congenital Heart Disease
  • Surgical Anatomy

Background:

  • Atrioventricular septal defect (AVSD) encompasses a spectrum of cardiac malformations.
  • The form with only a ventricular component of septal deficiency is rare.

Purpose of the Study:

  • To elucidate the surgical morphology of isolated ventricular septal defects in AVSD.
  • To compare this rare form with other AVSD subtypes.

Main Methods:

  • Examination of 78 cardiac specimens with atrioventricular septal defect.
  • Categorization into complete, partial, ostium primum, and isolated ventricular forms.

Main Results:

  • Hearts with isolated ventricular AVSD showed the mildest ventricular deformity.
  • These hearts exhibited a common atrioventricular junction and a 5-leaflet valve.
  • Characteristic "upwardly" displaced bridging leaflets were observed.

Conclusions:

  • Isolated ventricular AVSD may represent the mildest spectrum of atrioventricular septal defects.
  • Upwardly displaced leaflets pose a risk for postoperative valve dysfunction.
Abstract

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