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Isolation, Expansion, and Adipogenic Induction of CD34+CD31+ Endothelial Cells from Human Omental and Subcutaneous Adipose Tissue
Published on: July 17, 2018
Adipogenic risk factor differences between Korean and white adults--potential role of plasma free fatty acid and
Sangyeoup Lee1, Michael D Jensen
1Center for Obesity, Nutrition and Metabolism and Department of Family Medicine, Pusan National University Hospital, Pusan National University, Busan 602739, South Korea.
Abstract:
Asian adults are at greater risk for metabolic abnormalities (insulin resistance, dyslipidemia) at the same body mass index (BMI) than are whites. Elevated free fatty acids (FFA) and decreased adiponectin are linked with these same metabolic abnormalities. We tested the hypothesis that fasting plasma FFA are greater and adiponectin concentrations are lower in Korean than white adults matched for age, sex, and BMI. Plasma FFA and adiponectin concentrations were analyzed using a microfluorometric assay and radioimmunoassay, respectively. Fasting plasma FFA concentrations were not different (P = .51) between Korean and white subjects (208 [183-232] vs 215 [168-262] mumol/L, median and 95% confidence interval). Despite similar body composition in the 2 groups, the plasma adiponectin concentrations in Koreans were significantly lower than those in whites in men, women, and total subgroups (adjusted mean +/- SEM: 4.9 +/- 0.8 vs 9.1 +/- 0.8 microg/mL, P = .004; 8.9 +/- 1.0 vs 13.2 +/- 1.0 microg/mL, P = .006; and 6.5 +/- 0.6 vs 11.1 +/- 0.6 microg/mL, P
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