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Perinatal mortality in pregestational diabetes
1Perinatal Division, Helen Schneider Hospital for Women, Rabin Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Petah Tiqwa, Israel.
Summary
Perinatal mortality is high in pregnancies with pregestational diabetes due to poor glycemic control and unplanned pregnancies. Type 2 diabetes poses risks similar to type 1, highlighting the need for prevention strategies.
Area of Science:
- Obstetrics and Gynecology
- Endocrinology
- Public Health
Background:
- Perinatal mortality (PNM) rates are elevated in pregnancies with pregestational diabetes compared to the general population.
- Increasing prevalence of type 2 diabetes in pregnancy, often underestimated in risk.
- Both type 1 and type 2 pregestational diabetes are associated with significant PNM risks.
Purpose of the Study:
- To review the current epidemiology of PNM in pregestational diabetes.
- To explore the etiological factors contributing to PNM in these pregnancies.
- To outline evidence-based recommendations for PNM prevention.
Main Methods:
- Literature review of recent studies on pregestational diabetes and perinatal outcomes.
- Analysis of epidemiological data concerning PNM rates.
- Synthesis of etiological factors and risk assessment.
Main Results:
- Pregnancies with pregestational diabetes exhibit significantly higher PNM rates.
- Suboptimal glycemic control and unplanned pregnancies are key contributing factors.
- Type 2 diabetes in pregnancy is associated with PNM rates comparable to type 1 diabetes.
Conclusions:
- Effective glycemic control and family planning are crucial for reducing PNM.
- Increased awareness and management strategies are needed for type 2 diabetes in pregnancy.
- Comprehensive prevention approaches are essential for improving outcomes in diabetic pregnancies.
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