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Updated: Jun 26, 2026
Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model
Published on: November 4, 2022
Brain metastases from prostate adenocarcinoma
J E Castro Gómez1, U Anido Herranz, A Carballo Castro
1Radiation Oncology Department, Clinical University Hospital of Santiago de Compostela, Santiago de Compostela, La Coruña, Spain. quiquertp@yahoo.es
Abstract:
Brain metastases of prostate adenocarcinoma are rare. We report a case of brain metastases from prostate adenocarcinoma 15 months after the diagnosis of the primary tumour. The patient had headache and one solitary metastasis upon magnetic resonance imaging (MRI). The biopsy performed showed metastatic prostate adenocarcinoma. He was treated with surgery and cranial irradiation.
Insights
Brain metastases from prostate adenocarcinoma are rare. This case highlights a solitary brain metastasis 15 months post-diagnosis, treated with surgery and irradiation.
Area of Science:
- Neuro-oncology
- Urologic oncology
- Pathology
Background:
- Prostate adenocarcinoma is a common cancer in men.
- Brain metastases are an uncommon presentation of advanced prostate cancer.
- Early detection and treatment are crucial for managing metastatic disease.
Observation:
- A patient presented with headache 15 months after prostate adenocarcinoma diagnosis.
- Magnetic resonance imaging (MRI) revealed a single, isolated brain lesion.
- Biopsy confirmed the lesion as metastatic prostate adenocarcinoma.
Findings:
- The case illustrates a rare instance of solitary brain metastasis from prostate cancer.
- The metastasis was detected 15 months after the primary tumor diagnosis.
- Histopathological examination confirmed the metastatic origin.
Implications:
- This case underscores the importance of considering brain metastases in prostate cancer patients with neurological symptoms.
- Surgical resection followed by cranial irradiation can be a viable treatment option.
- Further research into the mechanisms and management of rare brain metastases is warranted.
