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Emerging paradigms in cancer genetics: some important findings from high-density single nucleotide polymorphism array

Manny D Bacolod1, Gunter S Schemmann, Sarah F Giardina

  • 1Department of Microbiology, Weill Medical College of Cornell University, New York, NY 10021, USA. barany@med.cornell.edu

Cancer Research
|January 22, 2009
PubMed
Summary

Autozygosity, long homozygous stretches from parental ancestry, may increase cancer risk. This genomic feature, along with somatic uniparental disomy, influences cancer predisposition and progression.

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