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Symplastic glomus tumor: a case report.

Yosep Chong¹, Minseob Eom, Hee-Joon Min

¹Department of Pathology, Yonsei University, Wonju College of Medicine, Wonju, Korea.

The American Journal of Dermatopathology

|January 22, 2009

Summary

This summary is machine-generated.

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Symplastic glomus tumors exhibit significant nuclear atypia but behave benignly. This rare tumor presents a diagnostic challenge for pathologists due to its high nuclear grade.

Area of Science:

Surgical pathology
Dermatopathology
Oncology

Background:

Glomus tumors are typically benign neoplasms originating from the glomus body.
Symplastic glomus tumors are a rare variant characterized by high-grade nuclear pleomorphism.
Distinguishing these from malignant tumors is crucial for appropriate patient management.

Observation:

The case involves a 44-year-old woman with a glomus tumor on her right index finger tip.
The tumor displayed marked nuclear atypia and pleomorphism, consistent with a symplastic glomus tumor.
No other malignant features such as infiltrative growth or necrosis were identified.

Findings:

Symplastic glomus tumors are defined by high-grade nuclear pleomorphism without other malignant indicators.

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Despite concerning nuclear features, these tumors demonstrate benign biologic behavior.

Only 11 cases have been previously reported in the English literature, highlighting their rarity.

Implications:

Pathologists must be aware of symplastic glomus tumors to avoid misdiagnosis of malignancy.
Accurate identification ensures appropriate clinical management, avoiding overly aggressive treatment.
Further case reporting and research can improve understanding of this rare entity.